Personal Information

Dr. Dipak Gayen

Assistant Professor
Department of Biochemistry

M.Sc. (Biochemistry; Calcutta University), Ph.D. (Biochemistry; Calcutta University), Postdoctoral Training (NIPGR, New Delhi; Cornell University, Ithaca, USA), INSA-Young Scientist, NASI-Young Scientist, Fulbright Fellow.

dipak.gayen@curaj.ac.in

9836079405

Genomics, proteomics, molecular biology and genetic engineering of plant

 

 

 

 

  • Assistant Professor (Jul 2019 – till present)- Department of Biochemistry, School of Life Sciences, Central University of Rajasthan, Kishangarh, Ajmer, India.
  • Fulbright Postdoctoral Fellow -Cornell University, Ithaca, NY, USA
  • National Postdoctoral Fellow -National Institute of Plant Genome Research, New Delhi
  • DBT-Research Associate - National Institute of Plant Genome Research, New Delhi
  • Doctor of Philosophy (PhD) in Biochemistry- University of Calcutta, India
  • M.Sc. in Biochemistry, University of Calcutta, India
  • B.Sc. (Hons.) in Chemistry, University of Calcutta, India

 

 

Dr. Gayen has expertise in the field of genomics, proteomics, metabolomics, miRNA and genetic engineering. In his work, he has gainfully combined his expertise in the area of plant molecular biology, particularly nutritional genomics with the techniques of cell biology. Dr. Gayen has also made significant progress in comprehensive analysis and characterization of the mitochondrial and chloroplast proteome for dissecting the molecular stress adaptation mechanism under dehydration in crop plants.

Dr. Gayen is presently involved in (i) protein homeostasis of chloroplast and mitochondria through protease system (ii) functional characterization novel stress responsive candidate genes of chloroplast and mitochondria and (iii) post-translational modification (phosphoproteomics) in response to stress (iv) CRISPR-Cas mediated genome editing. The major target is to identify the regulatory pathways which would provide direction for designing improved crops for sustainable agriculture.

Research award:

  1. INSA Medal for Young Scientist Award (2017)
  2. NASI-Young Scientist Platinum Jubilee Award (2018)
  3. Fulbright Fellow (2018)
  4. NASI Member

 

 

 

S. No. Authors Title of Article Journal/Conference Details Journal/Conference Publication Year
1

 

  PUBLICATIONS

Malviya, R., Dey, S., Pandey, A. and Gayen, D.Genome-wide identification and expression pattern analysis of lipoxygenase genes of chickpea (Cicer arietinum L.) in response to accelerated aging. Gene, 2023, 874, p.147482.

Pandey A, Sharma P, Mishra D, Dey S, Malviya R, Gayen D. Genome-wide identification of the fibrillin gene family in chickpea (Cicer arietinum L.) and its response to drought stress. International Journal of Biological Macromolecule 2023, 234,123757.

Sharma P, Pandey A, Malviya R, Dey S, Karmakar S. Gayen, D, Genome editing for improving nutritional quality, post-harvest shelf life and stress tolerance of fruits, vegetables, and ornamentals. Frontiers in Genome Editing, 2023.5.

Lande, N.V., Barua, P., Gayen, D., Wardhan, V., Jeevaraj, T., Kumar, S., Chakraborty, S. and Chakraborty, N., Dehydration‐responsive chickpea chloroplast protein, CaPDZ1, confers dehydration tolerance by improving photosynthesis, Physiologia Plantarum, 174(1), p.e13613

Sharma P, Gayen D. Plant protease as regulator and signaling molecule for enhancing environmental stress-tolerance. Plant Cell Report, 2021, 40 (11), 2081-2095.

Lande N.V, Barua P, Gayen D, Kumar S, Varshney S, Sengupta S, Chakraborty S, Chakraborty N. Dehydration-induced alterations in chloroplast proteome and reprogramming of cellular metabolism in developing chickpea delineate interrelated adaptive responses, Plant Physiology and Biochemistry, 2020, 337-348.

Lande N.V, Barua P, Gayen D, Chakraborty S, Chakraborty N. Proteomic dissection of the chloroplast: moving beyond photosynthesis, Chakraborty. Journal of Proteomics, 2019.

Karmakar S, Datta K, Molla K.A, Gayen D, Karmakar A, Das K, Sarkar S.N,Datta S.K. Proteo-metabolomic investigation of transgenic rice unravels metabolic alterations and accumulation of novel proteins potentially involved in defence against Rhizoctonia solani, Scientific Report, (2019), 9, 1.

Karmakar S, Molla K.A, Gayen D, Karmakar A, Das K, Sarkar S.N, Datta K, Datta S.K. Development of a rapid and highly efficient Agrobacterium-mediated transformation system for pigeon pea [Cajanus cajan (L.) Millsp], GM Crops and Food, 2019, 10, 115-138.

Gayen D, Barua P, Lande N.V, Varshney S, Sengupta S, Chakraborty S, Chakraborty N. Dehydration-responsive alterations in the chloroplast proteome and cell metabolomic profile of rice reveals key stress adaptation responses. Environmental and Experimental Botany, 2019, 160: 12-24.

Gayen D, Gayali S, Barua P, Lande N.V,  Varshney S, Sengupta S, Chakraborty S, Chakraborty N. Dehydration-induced proteomic landscape of mitochondria in chickpea reveals large-scale coordination of key biological processes. Journal of Proteomics, 2019, 192, 267-279.

Barua P, Lande N.V, Subba P, Gayen D, Pinto S, Keshava Prasad T.S, Chakraborty S, Chakraborty N. Dehydration-responsive nuclear proteome landscape of chickpea (Cicer arietinum L.) reveals phosphorylation-mediated regulation of stress response. Plant Cell & Environment, 2019, 42: 230-244.

Lande N.V, Subba P, Barua P, Gayen D, Chakraborty, S, Chakraborty N. Dissecting the chloroplast proteome of chickpea provides new insights into classical and non-classical functions. Journal of Proteomics, 2017, 165:11-20.

Gayen D, Ghosh S, Paul S, Sarkar S.N, Datta S.K, Datta K. Metabolic regulation of carotenoid-enriched Golden rice line. Frontiers in Plant Science, 2016, 7:1622.

Paul S*, Gayen D*, Datta S.K, Datta K. Analysis of high iron rice lines reveals new miRNAs that target iron transporters in roots Journal of Experimental Botany, 2016, 67: 5811–5824. (*Equal contribution).

Gayen D, Paul S, Datta S.K, Datta K. Comparative nutritional compositions and proteomics analysis of transgenic Xa21 rice seeds compared to conventional rice. Food Chemistry, 2016, 203: 301-307.

Rathi D*, Gayen D*, Gayali S, Chakraborty S, Chakraborty N. Legume proteomics: progress, prospects and challenges. Proteomics, 2016, 16: 310-327. (* Equal contribution).

Gayen D, Ali N, Sarkar S.N, Datta S.K, Datta K. Down regulation of lipoxygenase reduces degradation of carotenoids of golden rice during storage. Planta, 2015, 242: 353-363.

Paul S*, Gayen D*, Datta S.K, Datta K. Dissecting root proteome of transgenic rice cultivars unravels metabolic alterations and accumulation of novel stress responsive proteins under drought stress. Plant Science, 2015, 234: 133-143. (*Equal contribution).

Gayen D, Ali N, Ganguly M, Paul S, Datta K, Datta S.K.  RNAi mediated silencing of lipoxygenase gene to maintain rice grain nutritional quality and viability during storage. Plant Cell Tissue and Organ Culture, 2014, 118: 229-243.

Ali N, Paul S, Gayen D, Sarkar S.N, Datta SK, Datta K. RNAi mediated down regulation of myo-inositol-3 phosphate synthase to generate low phytate rice. Rice, 2013, 6:1-12.

Ali N, Paul S, Gayen D, Sarkar S.N, Datta K, Datta S.K. Development of low phytate indica rice cultivar by RNAi mediated silencing of inositol 1,3,4,5,6 penta kis phosphate 2- kinase gene (IPK1) using Oleosin-18 promoter. Plos One, 2013, 8: 1-12.

Gayen D, Sarkar S.N, Datta S.K, Datta K. Comparative analysis of nutritional compositions of transgenic high iron rice with its non- transgenic counterpart. Food Chemistry, 2013, 138: 835-840.

Paul S, Ali N, Gayen D, Datta S.K, Datta K. Molecular breeding of Osfer 2 gene to increase iron nutrition in rice grain. GM Crops Food, 2012, 3:310-316.

Ganguly M, Datta K, Roychoudhury A, Gayen D, Sengupta D.N, Datta S.K. Overexpression of Rab16A gene in indica rice variety for generating enhanced salt tolerance. Plant signalling & Behavior, 2012, 7: 502 -509.

BOOK CHAPTER

 

Barua P, Gayen D, Lande N.V, Chakraborty S , Chakraborty N. Screening of the global proteomic profile and identification of stress-responsive proteins using two-dimensional electrophoresis Methods in Molecular Biology, 2017, 1631:163-179.

Barua P, Gayen D, Lande N. V, Chakraborty S, Chakraborty N. The Role of Plasma Membrane Proteins in Tolerance of Dehydration in the Plant Cell. In Approaches in enhancing abiotic stress tolerance to plants. CRC Press, UK. ISBN 9780815346425. 2019.

Mondal S, Gayen D*, Karmakar S (2020) Improvement of nutritional quality of rice seed through classical breeding and advance genetic engineering Rice Research for Quality Improvement: Genomics and Genetic Engineering; Springer. https://doi.org/10.1007/978-981-15-5337-0_23 P.541-562 (*corresponding author).

Gayen D*, Karmakar S (2021) Designing, Performing, and Analyzing CRISPR-Cas9-Mediated Genome EditingGenome editing Experiments in Leguminous Plant. Springer . (*corresponding author).

Dey S, Malviya R and Gayen D (2022) Understanding Abiotic Stress Tolerance in Cereals Through Genomics and Proteomics Approaches. Springer Nature (In press).

Majumder, S., Datta, K., Gayen, D., Paul, S., Ali, N., Ghosh, S., Karmakar, A., Bhattacharya, S., Sengupta, S. and Datta, S.K., 2022. Biofortified Crops–Boon for Nutritional Security.

 

 

 

1. UGC Start UP- 10 lakh " Identification and functional characterization of chloroplast Clp protease from chickpea (Cicer arietinum L.) in response to heat stress ."(On-going)

2. SERB-SRG-30 lakh "Identification and functional characterization of novel protease for development of dehydration tolerance in chickpea (Cicer arietinum L.)." (Completed)

3. SERB-Core Grant-48 lakh "Unravelling the role of endoplasmic reticulum membrane protein in drought-induced unfolded protein response for developing stress-resilient chickpea (Cicer arietinum L.)". (March 2024-March 2027)....

 

 

Attended

1. Frontiers in Modern biology 2012 (FIMB-2012) organised by IISER-kolkata on 4-5th Feb, 2012

2. 100th Science congress organised by Science congress association on 3-7 Jan, 2013.

3. Plant Diversity and Resources: Evaluation, Analysis, Stress and challenges and Paleophytodiversity: its Aspects and prospect organised by Botanical Society of Bengal on 20-22nd December, 2011.

4. International Plant Nutrition Colloquium held on 19-22 August, 2013, Istanbul/ Turkey.

5. International conference on functional and interaction proteomics: Application in Food & Health, New Delhi, December 14-17, 2016.

6. International Conference on Proteomics in Health and Disease, ILS, Bhubaneswar, Nov 30th-Dec 2nd, 2017.

7. Plant Biotechnology and its relevance to food security organized by Calcutta University on 23rd August 2008 supported by DBT, Govt. of India.

8. 7Th pacific rim conference on Biotechnology of Bacillus thuringiensis and its environmental impact held at National Agricultural Science Centre, DPS Marg, New Delhi on 25-28 November, 2009.

9. Genomics Research and Impact in Plant System organised by Centre of Advanced Study, Botany, Calcutta University on 21st March, 2011.

10. Silver Jubilee Celebration of the Plant Physiology Forum organised by Plant Physiology Forum in association with Visva Bharati University and AICBA on 10th April, 2009.

 

 

Organized

Biotechnology for Crop Resilience & Sustainability in Post COVID-19 Era, 5th August 2020 at Dept of Biochemistry, CURAJ

Advances on Genomics Research of Crop, 16th Oct 2019, at Dept of Biochemistry, CURAJ

 

 

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